What is Asherman’s Syndrome & How Does it Impact Fertility?

June 2023 (2 min read)

There are many uterine conditions that can impact fertility.

Asherman’s syndrome is a condition in which scar tissue forms in the uterus. This scar tissue can block the fallopian tubes, making it difficult for sperm to reach the egg or for the fertilised egg to implant.

There is no exact number of women in the UK who experience Asherman’s syndrome, as it is often misdiagnosed or not diagnosed at all.

However, it is estimated that around 1 in 1,000 women in the UK may have the condition. Asherman’s syndrome is more common in women who have had a D&C (dilation and curettage) procedure, as this can damage the lining of the uterus and lead to the formation of scar tissue. The condition can also be caused by pelvic infections, childbirth, and other medical procedures.

There are no non-invasive treatments or drugs that can cure Asherman’s syndrome. However, there are a number of treatments that can help to improve the symptoms and increase the chances of getting pregnant.

Hormone therapy: Hormone therapy can help to reduce the amount of scar tissue and improve the lining of the uterus. Hormone therapy may include:

Oral contraceptives: These pills contain a combination of estrogen and progestin hormones. They can help to reduce the amount of scar tissue and improve the lining of the uterus.

Progestin-only therapy: This type of therapy uses progestin hormones to reduce the amount of scar tissue and improve the lining of the uterus. Progestin-only therapy may include:

Injectable progestin: This medication is injected into the muscle once a month.

Implantable progestin: This small rod is inserted under the skin of the arm and releases progestin hormones over a period of three years.

Intrauterine device (IUD) with levonorgestrel: This IUD releases progestin hormones directly into the uterus.

Gonadotropin-releasing hormone (GnRH) agonists: These medications stop the production of estrogen and progesterone hormones, which can lead to a temporary menopause. GnRH agonists are usually used for short-term treatment of Asherman’s syndrome.

Surgery: Surgery is the most common treatment for Asherman’s syndrome. The goal of surgery is to remove the scar tissue and restore the normal shape and function of the uterus. Surgery may be performed using laparoscopy or hysteroscopy.

Fertility treatments: If you have Asherman’s syndrome and are having difficulty getting pregnant, you may need fertility treatments. Fertility treatments may include:

In vitro fertilization (IVF): IVF is a procedure in which eggs are removed from the ovaries and fertilized with sperm in a laboratory. The fertilized eggs are then transferred to the uterus.

Intracytoplasmic sperm injection (ICSI): ICSI is a type of IVF in which a single sperm is injected directly into an egg.

The best treatment for Asherman’s syndrome will vary depending on the severity of the condition and your individual needs. It is important to talk to a doctor about the best treatment options for you.

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